Interchangeability of Generic Drugs: A Nonparametric Pharmacokinetic Model of Gabapentin Generic Drugs
نویسندگان
چکیده
منابع مشابه
The Interchangeability of Innovator and Generic Drugs
Submit Manuscript | http://medcraveonline.com Drug Products with Therapeutic Equivalence Evaluation (Orange Book) [2]. Generic drugs offer a powerful approach to cost savings for the patients. As a result patient compliance to the treatment increases [1,2]. In the year 2008 alone, generic drugs accounted for 69% of all prescriptions dispensed in the USA, yet only 16% of the cost in US dollar we...
متن کاملBioequivalence of generic drugs.
Generic drugs are bioequivalent to the original brand; this is a prerequisite for marketing approval. It is theoretically possible that one generic drug may overestimate the pharmacokinetic (PK) parameters of the original and another generic may underestimate these PK parameters; in consequence, these 2 generics may not be bioequivalent between themselves. The result could be loss of efficacy o...
متن کاملMake up a missed lesson‐New policy to ensure the interchangeability of generic drugs in China
Generic drugs should be interchangeable with originators in terms of quality and efficacy. With relative lower prices, generic drugs are playing an important role in controlling health expenditures and ensuring access. However, the widespread understanding of "cheap price equals low quality" has a negative impact on the acceptance of generic drugs. In China, medical doctors doubt the efficacy a...
متن کاملThe concept of: Generic drugs and patented drugs vs. brand name drugs and non-proprietary (generic) name drugs
Time and again the importance of generic prescribing has been emphasized, primarily to reduce the cost of drugs (Mukherjee, 2013). There are two concepts to be understood here, one is generic vs. patented drugs and the other is a drug’s “brand name” vs. “non-proprietary name” or “generic name.” Although, our article primarily describes the Indian scenario, it can be extrapolated to other countr...
متن کاملGeneric versus brand-name drugs
What?s in a name? A brand-name drug and its generic counterpart are chemically the same. They may have different names, colors, and shapes, but the United States Food and Drug Administration (FDA) requires generic drugs to share several similarities as the brand-name counterparts (more on this later). And, while there are some differences, generics don?t really change the effectiveness of the d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 2018
ISSN: 0009-9236
DOI: 10.1002/cpt.1023